TargetMol

CP 81282

Product Code:
 
TAR-T31033
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31033-5mg5mg£930.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T31033-50mg50mg£1,821.00
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Quantity:
TAR-T31033-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
CP 81282 inhibits human renin and endothiapepsin.
CAS:
121584-61-0
Formula:
C32H47F2N5O6
Molecular Weight:
635.754
Purity:
0.98
SMILES:
CCCC[C@H](N[C@@H](CC1CCCCC1)C(=O)C(F)(F)C(=O)NC)C(=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1

References

1. Aguilar CF, Cronin NB, Badasso M, Dreyer T, Newman MP, Cooper JB, Hoover DJ, Wood SP, Johnson MS, Blundell TL. The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae. J Mol Biol. 1997 Apr 11;267(4):899-915. PubMed PMID: 9135120. 2. Badasso M, Wood SP, Aguilar C, Cooper JB, Blundell TL, Dreyer T. Crystallization and preliminary crystallographic characterization of aspartic proteinase-A from baker's yeast and its complexes with inhibitors. J Mol Biol. 1993 Jul 20;232(2):701-3. PubMed PMID: 8345528. 3. Veerapandian B, Cooper JB, Sali A, Blundell TL, Rosati RL, Dominy BW, Damon DB, Hoover DJ. Direct observation by X-ray analysis of the tetrahedral "intermediate" of aspartic proteinases. Protein Sci. 1992 Mar;1(3):322-8. PubMed PMID: 1304340; PubMed Central PMCID: PMC2142209. 4. Hoover DJ, Veerapandian B, Cooper JB, Damon DB, Dominy BW, Rosati RL, Blundell TL. X-ray analysis of a difluorostatone renin inhibitor bound as the tetrahedral hydrate to the aspartic protease endothiapepsin. Adv Exp Med Biol. 1991;306:269-73. PubMed PMID: 1812716.