TargetMol

CP-195543

Product Code:
 
TAR-T31042
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31042-5mg5mg£850.00
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Quantity:
TAR-T31042-50mg50mg£1,661.00
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Quantity:
TAR-T31042-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
CP-195543 is an effective leukotriene B4 antagonist for the treatment of inflammatory diseases.
CAS:
204981-48-6
Formula:
C24H19F3O4
Molecular Weight:
428.407
Purity:
0.98
SMILES:
O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F

References

1. Fischer L, Haag-Diergarten S, Scharrer E, Lutz TA. Leukotriene and purinergic receptors are involved in the hyperpolarizing effect of glucagon in liver cells. Biochim Biophys Acta. 2005 May 15;1669(1):26-33. PubMed PMID: 15842996. 2. Khojasteh-Bakht SC, Rossulek MI, Fouda HG, Prakash C. Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543. Xenobiotica. 2003 Dec;33(12):1201-10. PubMed PMID: 14742142. 3. Yokomizo T, Kato K, Hagiya H, Izumi T, Shimizu T. Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2. J Biol Chem. 2001 Apr 13;276(15):12454-9. Epub 2001 Jan 18. PubMed PMID: 11278893. 4. Dalvie DK, O'Donnell JP. Metabolism of CP-195,543, a leukotriene B4 receptor antagonist, in the Long-Evans rat and Cynomolgus monkey. Xenobiotica. 1999 Nov;29(11):1123-40. PubMed PMID: 10598747.