TargetMol

cvxIAA

Product Code:
 
TAR-T31123
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31123-5mg5mg£850.00
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TAR-T31123-50mg50mg£1,661.00
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TAR-T31123-100mg100mg£2,079.00
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Further Information

Bioactivity:
cvxIAA is an orthogonal auxin-TIR1 receptor pair. cvxIAA triggers auxin signaling without interfering with endogenous auxin or TIR1/AFBs. cvxIAA hijacked the downstream auxin signaling in vivo both at the transcriptomic level and in specific developmental contexts, only in the presence of a complementary, concave TIR1 (ccvTIR1) receptor. cvxIAA-ccvTIR1 system serves as a powerful tool for solving outstanding questions in auxin biology and for precise manipulation of auxin-mediated processes as a controllable switch.
CAS:
2127037-35-6
Formula:
C17H15NO3
Molecular Weight:
281.311
Purity:
0.98
SMILES:
COc1cccc(c1)-c1ccc2[nH]cc(CC(O)=O)c2c1

References

1. Yamada R, Murai K, Uchida N, Takahashi K, Iwasaki R, Tada Y, Kinoshita T, Itami K, Torii KU, Hagihara S. A Super Strong Engineered Auxin-TIR1 Pair. Plant Cell Physiol. 2018 Aug 1;59(8):1538-1544. doi: 10.1093/pcp/pcy127. PubMed PMID: 29986114; PubMed Central PMCID: PMC6084576. 2. Uchida N, Takahashi K, Iwasaki R, Yamada R, Yoshimura M, Endo TA, Kimura S, Zhang H, Nomoto M, Tada Y, Kinoshita T, Itami K, Hagihara S, Torii KU. Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair. Nat Chem Biol. 2018 Mar;14(3):299-305. doi: 10.1038/nchembio.2555. Epub 2018 Jan 22. PubMed PMID: 29355850; PubMed Central PMCID: PMC5812785.