TargetMol

Ecadotril

Product Code:
 
TAR-T31598
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31598-5mg5mg£850.00
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TAR-T31598-50mg50mg£1,661.00
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TAR-T31598-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ecadotril is a neutral endopeptidase (NEP) inhibitor, which plays an anti hypertensive role.
CAS:
112573-73-6
Formula:
C21H23NO4S
Molecular Weight:
385.48
Purity:
0.98
SMILES:
CC(=O)SC[C@@H](Cc1ccccc1)C(=O)NCC(=O)OCc1ccccc1

References

1. S?ez J, Cifuentes L. Is racecadotril effective for acute diarrhea in children? -First update. Version 2. Medwave. 2016 May 6 [revised 2016 May 24];16(Suppl2):e6438. doi: 10.5867/medwave.2016.6438. Spanish, English. PubMed PMID: 26731112. 2. Racecadotril + ACE inhibitors: angioedema. Prescrire Int. 2016 Mar;25(169):71. PubMed PMID: 27213193. 3. Chiguru V, Lingesh A, R S, N S. Forced degradation study of racecadotril: Effect of co-solvent, characterization of degradation products by UHPLC-Q-TOF-MS/MS, NMR and cytotoxicity assay. J Pharm Biomed Anal. 2016 May 6;128:9-17. doi: 10.1016/j.jpba.2016.05.008. [Epub ahead of print] PubMed PMID: 27209450. 4. Griggs DW, Prinsen MJ, Oliva J, Campbell MA, Arnett SD, Tajfirouz D, Ruminski PG, Yu Y, Bond BR, Ji Y, Neckermann G, Choy RK, de Hostos E, Meyers MJ. Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea. J Pharmacol Exp Ther. 2016 May;357(2):423-31. doi: 10.1124/jpet.115.231167. Epub 2016 Feb 23. PubMed PMID: 26907621; PubMed Central PMCID: PMC4851326.