TargetMol

Erythrityl Tetranitrate

Product Code:
 
TAR-T31671
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31671-5mg5mg£850.00
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TAR-T31671-50mg50mg£1,661.00
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Quantity:
TAR-T31671-100mg100mg£2,079.00
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  • Further Information
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Further Information

Bioactivity:
Erythrityl Tetranitrate is a vasodilator with general properties similar to nitroglycerin. Like many nitrate esters, ETN acts as a vasodilator, and was the active ingredient in the original "sustained release" tablets, made under a process patent in the early 50s. Ingesting ETN or prolonged skin contact can lead to absorption and what is known as a "nitro headache".
CAS:
7297-25-8
Formula:
C4H6N4O12
Molecular Weight:
302.108
Purity:
0.98
SMILES:
[O-][N+](=O)OC[C@@H](O[N+]([O-])=O)[C@H](CO[N+]([O-])=O)O[N+]([O-])=O

References

1. Nakamura Y, Haffty BG, Long RA, Hull HJ, Starbuck RR, Spodick DH. Erythrityl tetranitrate compared with isosorbide dinitrate. Effects on systolic time intervals and nitrate modification of effects of food. Pharmacotherapy. 1983 Jul-Aug;3(4):230-4. PubMed PMID: 6351027. 2. Tomov I, Kaloianova A, Terzieva L, Elenkova A, Nikolov G. [Vasodilator treatment of chronic heart failure: a chronic double-blind trial with prazosin and erythrityl tetranitrate]. Vutr Boles. 1981;20(6):72-8. Bulgarian. PubMed PMID: 7039130. 3. Johnsson G, Henning M, Ablad B. Rate of onset of vasodilator effect of glyceryl trinitrate, propatylnitrate and erythrityl tetranitrate in man. Scand J Clin Lab Invest. 1965;17(6):600-6. PubMed PMID: 4955334. 4. Erythrityl tetranitrate; drug efficacy study implementation; revocation of exemption; opportunity for a hearing--FDA. Notice. Fed Regist. 1998 Jun 23;63(120):34188-90. PubMed PMID: 10180293.