TargetMol

Famotine hydrochloride

Product Code:
 
TAR-T31743
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31743-5mg5mg£850.00
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TAR-T31743-50mg50mg£1,661.00
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Quantity:
TAR-T31743-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Famotine Hydrochloride is a histamine H2 receptor antagonist that suppresses acid production in the stomach and commonly treats peptic ulcer disease and gastroesophageal reflux disease.
CAS:
10500-82-0
Formula:
C16H15Cl2NO
Molecular Weight:
308.2
Purity:
0.98
SMILES:
Cl.Clc1ccc(OCC2=NCCc3ccccc23)cc1

References

1. Smolinska S, Groeger D, Perez NR, Schiavi E, Ferstl R, Frei R, Konieczna P, Akdis CA, Jutel M, O?Mahony L. Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016 Jul;22(7):1575-86. doi: 10.1097/MIB.0000000000000825. PubMed PMID: 27271490. 2. Pahs L, Droege C, Kneale H, Pancioli A. A Novel Approach to the Treatment of Orolingual Angioedema After Tissue Plasminogen Activator Administration. Ann Emerg Med. 2016 May 10. pii: S0196-0644(16)00123-2. doi: 10.1016/j.annemergmed.2016.02.019. [Epub ahead of print] PubMed PMID: 27174372. 3. Litou C, Vertzoni M, Goumas C, Vasdekis V, Xu W, Kesisoglou F, Reppas C. Characteristics of the Human Upper Gastrointestinal Contents in the Fasted State Under Hypo- and A-chlorhydric Gastric Conditions Under Conditions of Typical Drug - Drug Interaction Studies. Pharm Res. 2016 Jun;33(6):1399-412. doi: 10.1007/s11095-016-1882-8. Epub 2016 Mar 14. PubMed PMID: 26975361. 4. Grosicki M, W?jcik T, Chlopicki S, Kie?-Kononowicz K. In vitro study of histamine and histamine receptor ligands influence on the adhesion of purified human eosinophils to endothelium. Eur J Pharmacol. 2016 Apr 15;777:49-59. doi: 10.1016/j.ejphar.2016.02.061. Epub 2016 Mar 3. PubMed PMID: 26939881.