TargetMol

Folligen

Product Code:
 
TAR-T31842
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T31842-5mg5mg£850.00
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Further Information

Bioactivity:
Folligen is a novel gonadotropin-releasing hormone analog against DMBA-induced tumours in the rat.
CAS:
103631-79-4
Formula:
C61H78N14O13
Molecular Weight:
1215.38
Purity:
0.98
SMILES:
CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CCC(=O)N1

References

1. Nicholson RI, K?ri G. Antitumour activity of folligen, a novel gonadotropin-releasing hormone analogue against DMBA-induced tumours in the rat. Tumour Biol. 1992;13(1-2):44-50. PubMed PMID: 1534181. 2. K?ri G, Balogh A, Sz?ke B, Tepl?n I, Csuka O. Gonadotropin-releasing hormone analogues inhibit cell proliferation and activate signal transduction pathways in MDA-MB-231 human breast cancer cell line. Tumour Biol. 1991;12(2):61-7. PubMed PMID: 1902971. 3. Tepl?n I. Peptides and antitumor activity. Development and investigation of some peptides with antitumor activity. Acta Biol Hung. 2000;51(1):1-29. Review. PubMed PMID: 10866357. 4. K?ri G, Balogh A, Horv?th A, Mez? I, Vad?sz Z, B?k?nyi G, Bajor T, V?ntus T, Tepl?n I, Horv?th J, et al. Novel antitumor peptide hormones and their effect on signal transduction. J Steroid Biochem Mol Biol. 1992 Sep;43(1-3):105-10. PubMed PMID: 1356011.