TargetMol

Fomocaine HCl

Product Code:
 
TAR-T31843
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31843-5mg5mg£850.00
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TAR-T31843-50mg50mg£1,661.00
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Quantity:
TAR-T31843-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fomocaine is an type of anaesthetic agent blocking voltage-gated Na(+) currents in neurons.
CAS:
56583-43-8
Formula:
C20H26ClNO2
Molecular Weight:
347.88
Purity:
0.98
SMILES:
Cl.C(CN1CCOCC1)Cc1ccc(COc2ccccc2)cc1

References

1. Schoenberger M, Damijonaitis A, Zhang Z, Nagel D, Trauner D. Development of a new photochromic ion channel blocker via azologization of fomocaine. ACS Chem Neurosci. 2014 Jul 16;5(7):514-8. doi: 10.1021/cn500070w. Epub 2014 Jun 5. PubMed PMID: 24856540; PubMed Central PMCID: PMC4102962. 2. Baumgart M, Feller C, Natura G, Dahse T, Schaible HG, Dahse I. Blockade of TTX-resistant and TTX-sensitive Na+ currents in cultured dorsal root ganglion neurons by fomocaine and the fomocaine derivative Oe 9000. Brain Res. 2010 Oct 28;1358:54-63. doi: 10.1016/j.brainres.2010.08.033. Epub 2010 Aug 19. PubMed PMID: 20727863. 3. Lupp A, Karge E, Dahse T, Glassl P, Jung B, Listing M, Seeling A, Wange J, Wennek-Klose J, Oelschl?ger H, Fleck C. A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part III. Arzneimittelforschung. 2007;57(11):685-8. doi: 10.1055/s-0031-1296668. Review. PubMed PMID: 18193689. 4. Lupp A, Karge E, Dahse T, Glassl P, Jung B, Listing M, Seeling A, Wange J, Wennek-Klose J, Oelschl?ger H, Fleck C. A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--part II. Arzneimittelforschung. 2007;57(10):633-40. PubMed PMID: 18074756.