TargetMol

Formycin B

Product Code:
 
TAR-T31852
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T31852-5mg5mg£850.00
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Further Information

Bioactivity:
Formycin B is a model nucleoside analog.
CAS:
13877-76-4
Formula:
C10H12N4O5
Molecular Weight:
268.229
Purity:
0.98
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1n[nH]c2c1[nH]cnc2=O

References

1. Wu X, Hui AC, Giacomini KM. Formycin B elimination from the cerebrospinal fluid of the rat. Pharm Res. 1993 Apr;10(4):611-5. PubMed PMID: 8483848. 2. Borgland SL, Parkinson FE. Uptake and release of [3H]formycin B via sodium-dependent nucleoside transporters in mouse leukemic L1210/MA27.1 cells. J Pharmacol Exp Ther. 1997 Apr;281(1):347-53. PubMed PMID: 9103516. 3. Burke T, Lee S, Ferguson PJ, Hammond JR. Interaction of 2',2'-difluorodeoxycytidine (gemcitabine) and formycin B with the Na+-dependent and -independent nucleoside transporters of Ehrlich ascites tumor cells. J Pharmacol Exp Ther. 1998 Sep;286(3):1333-40. PubMed PMID: 9732397. 4. Robinson N, Kaur K, Emmett K, Iovannisci DM, Ullman B. Biochemical genetic analysis of formycin B action in Leishmania donovani. J Biol Chem. 1984 Jun 25;259(12):7637-43. PubMed PMID: 6203896.