TargetMol

Galphimine B

Product Code:
 
TAR-T31903
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31903-5mg5mg£850.00
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  • Further Information
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Further Information

Bioactivity:
Galphimine B is a cyclodesiccated triterpenoid from Galphimia Glauca, which can regulate the synaptic transmission of dopaminergic ventral tegmental neurons and has a sedative effect.
CAS:
149199-48-4
Formula:
C30H44O7
Molecular Weight:
516.675
Purity:
0.98
SMILES:
[H][C@@]12C=CC(=O)OC[C@@]1(C[C@@H](O)[C@@]1([H])[C@@]2(C)CC[C@]2(C(=O)OC)[C@]1(C)CC[C@@]1(C)CC=C(C)C[C@@]21O)C(C)O

References

1. Jim?nez-Ferrer E, Herrera-Ruiz M, Ram?rez-Garc?a R, Herrera-Arellano A, Tortoriello J. Interaction of the natural anxiolytic Galphimine-B with serotonergic drugs on dorsal hippocampus in rats. J Ethnopharmacol. 2011 Sep 1;137(1):724-9. doi: 10.1016/j.jep.2011.06.029. Epub 2011 Jul 1. PubMed PMID: 21742023. 2. Lara-Ochoa F, Guill?n-Torres A, Espinosa-P?rez G, Ortega-Hern?ndez A. Conformational study of galphimines A and B. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Sep;61(11-12):2677-86. PubMed PMID: 15950532. 3. Osuna L, Moyano E, Mangas S, Bonfill M, Cusid? RM, Pi?ol MT, Zamilpa A, Tortoriello J, Palaz?n J. Immobilization of Galphimia glauca plant cell suspensions for the production of enhanced amounts of Galphimine-B. Planta Med. 2008 Jan;74(1):94-9. doi: 10.1055/s-2007-993763. Epub 2008 Jan 4. PubMed PMID: 18176908. 4. Prieto-G?mez B, Tortoriello J, V?zquez-Alvarez A, Reyes-V?zquez C. Galphimine B modulates synaptic transmission on dopaminergic ventral tegmental area neurons. Planta Med. 2003 Jan;69(1):38-43. PubMed PMID: 12567277.