TargetMol

GSK945237

Product Code:
 
TAR-T32011
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32011-5mg5mg£1,492.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T32011-50mg50mg£2,946.00
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Quantity:
TAR-T32011-100mg100mg£4,006.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GSK945237 is an effective bacterial type IIA topoisomerase inhibitor with good efficacy against both Gram-positive and Gram-negative, and shows good PK and in vivo efficacy characteristics.
CAS:
944406-54-6
Formula:
C24H26FN5O3
Molecular Weight:
451.502
Purity:
0.98
SMILES:
Fc1ccc2ccc(=O)n3C[C@@H](CN4CCC(CC4)NCc4cc5OCCOc5nn4)c1c23

References

1. Miles TJ, Hennessy AJ, Bax B, Brooks G, Brown BS, Brown P, Cailleau N, Chen D, Dabbs S, Davies DT, Esken JM, Giordano I, Hoover JL, Jones GE, Kusalakumari Sukmar SK, Markwell RE, Minthorn EA, Rittenhouse S, Gwynn MN, Pearson ND. Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases. Bioorg Med Chem Lett. 2016 Mar 31. pii: S0960-894X(16)30338-9. doi: 10.1016/j.bmcl.2016.03.106. [Epub ahead of print] PubMed PMID: 27055939.