TargetMol

ISF-402

Product Code:
 
TAR-T32199
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
ISF-402 is an insulin sensitizer that may be used in the treatment of type 2 diabetes, dispersing the hexamer insulin in vitro and enhancing the activity of the hexamer insulin more than the monomer liproline insulin.
CAS:
484649-95-8
Formula:
C19H31N7O7
Molecular Weight:
469.499
Purity:
0.98
SMILES:
CC(C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(O)=O

References

1. Paule SG, Nikolovski B, Ludeman J, Gray RE, Spiccia L, Zimmet PZ, Myers MA. Ability of GHTD-amide and analogs to enhance insulin activity through zinc chelation and dispersal of insulin oligomers. Peptides. 2009 Jun;30(6):1088-97. doi: 10.1016/j.peptides.2009.02.020. PubMed PMID: 19463741.