TargetMol

Jaspisamide A

Product Code:
 
TAR-T32270
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32270-5mg5mg£850.00
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Further Information

Bioactivity:
Jaspisamide A is an type of actin-binding protein.
CAS:
149420-76-8
Formula:
C45H62N4O12
Molecular Weight:
851.007
Purity:
0.98
SMILES:
COC(CC1OC(=O)CC(O)CC=C/C(=O)C(C)C(OC)c2coc(n2)-c2coc(n2)-c2coc(C=C/CCC1C)n2)C(C)CCC(=O)C(C)C(OC)C(C)C=CN(C)C=O

References

1. Tanaka J, Yan Y, Choi J, Bai J, Klenchin VA, Rayment I, Marriott G. Biomolecular mimicry in the actin cytoskeleton: mechanisms underlying the cytotoxicity of kabiramide C and related macrolides. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13851-6. Epub 2003 Nov 11. PubMed PMID: 14612571; PubMed Central PMCID: PMC283510. 2. Klenchin VA, Allingham JS, King R, Tanaka J, Marriott G, Rayment I. Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin. Nat Struct Biol. 2003 Dec;10(12):1058-63. Epub 2003 Oct 26. PubMed PMID: 14578936. 3. Kobayashi J, Murata O, Shigemori H. Jaspisamides A-C, new cytotoxic macrolides from the Okinawan sponge Jaspis sp. J Nat Prod. 1993 May;56(5):787-91. PubMed PMID: 8326327.