TargetMol

KS 502

Product Code:
 
TAR-T32422
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32422-5mg5mg£850.00
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Further Information

Bioactivity:
KS 502 interferes with calmodulin activation and is isolated from Sporothrix sp. KAC-1985.
CAS:
120634-85-7
Formula:
C34H48O12
Molecular Weight:
648.746
Purity:
0.98
SMILES:
CCCCCCCc1cc(O)cc(O[C@@H]2O[C@@H]([C@H](O)CO)[C@H](O)[C@H]2O)c1C(=O)Oc1cc(O)c(C(O)=O)c(CCCCCCC)c1

References

1. Nakanishi S, Ando K, Kawamoto I, Kase H. KS-501 and KS-502, new inhibitors of Ca2+ and calmodulin-dependent cyclic-nucleotide phosphodiesterase from Sporothrix sp. J Antibiot (Tokyo). 1989 Jul;42(7):1049-55. PubMed PMID: 2546910. 2. Yasuzawa T, Saitoh Y, Sano H. Structures of KS-501 and KS-502, the new inhibitors of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase. J Antibiot (Tokyo). 1990 Apr;43(4):336-43. PubMed PMID: 2161817. 3. Hait WN, Gesmonde J, Cheng E. Effects of KS-501, KS-502 and their enantiomers on calmodulin-sensitive enzyme activity and cellular proliferation. Biochem Pharmacol. 1995 Jun 29;50(1):69-74. PubMed PMID: 7605347.