TargetMol

L 650719

Product Code:
 
TAR-T32453
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T32453-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
L 650719 is a bioactive chemical.
CAS:
96803-89-3
Formula:
C8H7NO3S2
Molecular Weight:
229.27
Purity:
0.98
SMILES:
NS(=O)(=O)c1cc2ccc(O)cc2s1

References

1. Graham SL, Shepard KL, Anderson PS, Baldwin JJ, Best DB, Christy ME, Freedman MB, Gautheron P, Habecker CN, Hoffman JM, et al. Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity. J Med Chem. 1989 Dec;32(12):2548-54. PubMed PMID: 2585443. 2. Bar-Ilan A, Pessah NI, Maren TH. Ocular hypotensive activity and disposition of the topical carbonic anhydrase inhibitor 6-hydroxy-benzo[b]thiophene-2-sulfonamide, L-650,719, in the rabbit. J Ocul Pharmacol. 1989 Summer;5(2):99-110. PubMed PMID: 2754300. 3. Grove J, Gautheron P, Plazonnet B, Sugrue MF. Ocular distribution studies of the topical carbonic anhydrase inhibitors L-643,799 and L-650,719 and related alkyl prodrugs. J Ocul Pharmacol. 1988 Winter;4(4):279-90. PubMed PMID: 3246565. 4. Werner EB, Gerber DS, Yoder YJ. Effect of a topical carbonic anhydrase inhibitor, 6-hydroxybenzo[b]thiophene-2-sulfonamide, on intraocular pressure in normotensive subjects. Can J Ophthalmol. 1987 Oct;22(6):316-9. PubMed PMID: 3322537.