TargetMol

Lactandrate

Product Code:
 
TAR-T32526
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32526-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Lactandrate is a homo-aza-steroidal ester of p-bis(2-chloroethyl) amino phenyl acetic acid.
CAS:
43000-65-3
Formula:
C31H44Cl2N2O3
Molecular Weight:
563.6
Purity:
0.98
SMILES:
C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](CC[C@]34C)OC(=O)Cc3ccc(cc3)N(CCCl)CCCl)[C@@H]1CCC(=O)N2

References

1. Trafalis DT, Geromichalos GD, Koukoulitsa C, Papageorgiou A, Karamanakos P, Camoutsis C. Lactandrate: a D-homo-aza-androsterone alkylator in the treatment of breast cancer. Breast Cancer Res Treat. 2006 May;97(1):17-31. Epub 2005 Dec 1. PubMed PMID: 16319980. 2. Trafalis DT, Geromichalos GD, Bountouroglou N, Koumbi D, Kontos M, Sougias D, Dalezis P, Karamanakos P, Papageorgiou A, Camoutsis C, Athanassiou AE. A preclinical survey on the efficacy of lactandrate in the treatment of colon carcinoma. J BUON. 2005 Apr-Jun;10(2):227-34. PubMed PMID: 17343334. 3. Trafalis DT. Hybrid aza-steroid alkylators in the treatment of colon cancer. Cancer Lett. 2006 Nov 18;243(2):202-10. Epub 2006 Jan 18. PubMed PMID: 16412564.