TargetMol

Mersalyl

Product Code:
 
TAR-T33297
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T33297-5mg5mg£850.00
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Further Information

Bioactivity:
Mersalyl is an organic mercurial diuretic.
CAS:
492-18-2
Formula:
C13H16HgNNaO6
Molecular Weight:
505.854
Purity:
0.98
SMILES:
[Na+].COC(CNC(=O)c1ccccc1OCC(O)=O)C[Hg][O-]

References

Joseph SK, Ryan SV, Pierson S, Renard-Rooney D, Thomas AP. The effect of mersalyl on inositol trisphosphate receptor binding and ion channel function. J Biol Chem. 1995 Feb 24;270(8):3588-93. PubMed PMID: 7533153. Garc?a N, Mart?nez-Abundis E, Pav?n N, Ch?vez E. On the opening of an insensitive cyclosporin A non-specific pore by phenylarsine plus mersalyl. Cell Biochem Biophys. 2007;49(2):84-90. PubMed PMID: 17906363. Kolbe HV, Kadenbach B. Reaction of mersalyl with mitochondrial proteins under native and denaturing conditions as exemplified by the identification and isolation of the phosphate carrier. Hoppe Seylers Z Physiol Chem. 1981 Dec;362(12):1583-90. PubMed PMID: 7319473. Agani F, Semenza GL. Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity. Mol Pharmacol. 1998 Nov;54(5):749-54. PubMed PMID: 9804609.