TargetMol

MK-3281

Product Code:
 
TAR-T33432
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33432-5mg5mg£1,010.00
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Quantity:
TAR-T33432-50mg50mg£1,982.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T33432-100mg100mg£2,560.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MK-3281 is a potent, orally bioavailable hepatitis C virus NS5B polymerase finger-loop inhibitor. It is also an inhibitor of attractive molecular properties with good potency in HCV subgenomic replication trials and suitable for clinical candidates.
CAS:
886041-60-7
Formula:
C29H37N3O3
Molecular Weight:
475.633
Purity:
0.98
SMILES:
CN(C)CCN(C)C1COc2ccccc2-c2c(C3CCCCC3)c3ccc(cc3n2C1)C(O)=O

References

Narjes F, Crescenzi B, Ferrara M,et al.. Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase. J Med Chem. 2011 Jan 13;54(1):289-301. doi: 10.1021/jm1013105. Epub 2010 Dec 8. PubMed PMID: 21141896.