TargetMol

MK436

Product Code:
 
TAR-T33434
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33434-5mg5mg£850.00
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TAR-T33434-50mg50mg£1,661.00
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Quantity:
TAR-T33434-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MK436 is a therapeutic agent and an antigenic animal drug that is effective in the treatment of Trypanosoma cruzonii infection.
CAS:
33450-08-7
Formula:
C11H14N4O3
Molecular Weight:
250.258
Purity:
0.98
SMILES:
Cn1c(ncc1[N+]([O-])=O)C1=NOC2CCCCC12

References

Jennings FW. Chemotherapy of CNS-trypanosomiasis: combination chemotherapy with a 5-nitroimidazole (MK 436), an arsenical (Cymelarsan) and suramin. Trop Med Parasitol. 1991 Sep;42(3):157-60. PubMed PMID: 1801135. Andrade SG, Silva RC, Santiago CM. Treatment of chronic experimental Trypanosoma cruzi infections in mice with MK-436, a 2-substituted 5-nitroimidazole. Bull World Health Organ. 1989;67(5):509-14. PubMed PMID: 2515007; PubMed Central PMCID: PMC2491297. Jennings FW, Atouguia JM, Murray M. Topical chemotherapy for experimental murine African CNS-trypanosomiasis: the successful use of the arsenical, melarsoprol, combined with the 5-nitroimidazoles, fexinidazole or MK-436. Trop Med Int Health. 1996 Oct;1(5):590-8. PubMed PMID: 8911443. Andrade SG, Silva RC, Santiago CM, Freitas LA. Therapeutic action of MK-436 (2,5-nitroimidazole) on Trypanosoma cruzi infections in mice: a parasitological, serological, histopathological, and ultrastructural study. Bull World Health Organ. 1987;65(5):625-33. PubMed PMID: 3123082; PubMed Central PMCID: PMC2491062.