TargetMol

Nitromifene Citrate

Product Code:
 
TAR-T33688
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T33688-5mg5mg£850.00
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Further Information

Bioactivity:
Nitromifene Citrate is a nonsteroidal estrogen antagonist most commonly used as a research tool in animal studies.
CAS:
5863-35-4
Formula:
C33H36N2O11
Molecular Weight:
636.654
Purity:
0.98
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O.COc1ccc(cc1)C(=C(/c1ccccc1)[N+]([O-])=O)c1ccc(OCCN2CCCC2)cc1

References

Rudick CN, Woolley CS. Selective estrogen receptor modulators regulate phasic activation of hippocampal CA1 pyramidal cells by estrogen. Endocrinology. 2003 Jan;144(1):179-87. PubMed PMID: 12488344. Young EA, Altemus M, Parkison V, Shastry S. Effects of estrogen antagonists and agonists on the ACTH response to restraint stress in female rats. Neuropsychopharmacology. 2001 Dec;25(6):881-91. PubMed PMID: 11750181. Henley CL, Nunez AA, Clemens LG. Hormones of choice: the neuroendocrinology of partner preference in animals. Front Neuroendocrinol. 2011 Apr;32(2):146-54. doi: 10.1016/j.yfrne.2011.02.010. Epub 2011 Mar 4. Review. PubMed PMID: 21377487. Nakamura NH, McEwen BS. Changes in interneuronal phenotypes regulated by estradiol in the adult rat hippocampus: a potential role for neuropeptide Y. Neuroscience. 2005;136(1):357-69. Epub 2005 Sep 28. PubMed PMID: 16198490.