TargetMol

Nitroparacetamol

Product Code:
 
TAR-T33689
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33689-5mg5mg£850.00
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TAR-T33689-50mg50mg£1,661.00
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Quantity:
TAR-T33689-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Nitroparacetamol is nitric oxide (NO) donor and may be used to treat pain.
CAS:
326850-30-0
Formula:
C12H14N2O6
Molecular Weight:
282.252
Purity:
0.98
SMILES:
CC(=O)Nc1ccc(OC(=O)CCCO[N+]([O-])=O)cc1

References

Alfonso Romero-Sandoval E, Molina C, Herrero JF. Enhancement of the analgesic activity of paracetamol and nitroparacetamol by the oral administration of all-trans retinoic acid. Neuropharmacology. 2006 Sep;51(4):858-65. PubMed PMID: 16870215. Molina C, Herrero JF. Subeffective doses of nitroparacetamol (NCX-701) enhance the antinociceptive activity of the ??-adrenoceptor agonist medetomidine. Pharmacol Biochem Behav. 2011 Sep;99(3):385-90. doi: 10.1016/j.pbb.2011.05.022. PubMed PMID: 21640748. Romero-Sandoval EA, Curros-Criado MM, Gaitan G, Molina C, Herrero JF. Nitroparacetamol (NCX-701) and pain: first in a series of novel analgesics. CNS Drug Rev. 2007 Fall;13(3):279-95. Review. PubMed PMID: 17894645. Gait?n G, Ahuir FJ, Herrero JF. Enhancement of fentanyl antinociception by subeffective doses of nitroparacetamol (NCX-701) in acute nociception and in carrageenan-induced monoarthritis. Life Sci. 2005 May 20;77(1):85-95. PubMed PMID: 15848221.