TargetMol

o-Iodohippurate sodium

Product Code:
 
TAR-T33785
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T33785-5mg5mg£850.00
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Further Information

Bioactivity:
o-Iodohippurate sodium is an analogue of p-aminohippuric acid used to determine effective renal plasma flow. Labelled OIH has a higher clearance than other radiopharmaceutical yet developed and is extremely suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may exist in the urine after intravenous injection for 30 minutes.
CAS:
133-17-5
Formula:
C9H7INNaO3
Molecular Weight:
327.053
Purity:
0.98
SMILES:
[Na+].[O-]C(=O)CNC(=O)c1ccccc1I

References

Mukai T, Fujioka Y, Arano Y, Saji H. [Design of radiolabeled antibody fragments for tumor-selective radioactivity localization--brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity]. Yakugaku Zasshi. 2003 Aug;123(8):647-52. Review. Japanese. PubMed PMID: 12931660. Taylor A. Radionuclide renography: a personal approach. Semin Nucl Med. 1999 Apr;29(2):102-27. Review. PubMed PMID: 10321824. Fine EJ. Interventions in renal scintirenography. Semin Nucl Med. 1999 Apr;29(2):128-45. Review. PubMed PMID: 10321825. el Maghraby TA, van Eck-Smit BL, de Fijter JW, Pauwels EK. Quantitative scintigraphic parameters for the assessment of renal transplant patients. Eur J Radiol. 1998 Oct;28(3):256-69. Review. PubMed PMID: 9881262.