TargetMol

OptoDArG

Product Code:
 
TAR-T33814
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33814-5mg5mg£850.00
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Quantity:
TAR-T33814-50mg50mg£1,661.00
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Quantity:
TAR-T33814-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
OptoDArG is a diacylglycerol (DAG) photoswitch, which enables efficient control of TRPC3 by light.
CAS:
2230617-93-1
Formula:
C43H52N4O5
Molecular Weight:
704.912
Purity:
0.98
SMILES:
CCCCc1ccc(cc1)N=Nc1ccc(CCCC(=O)OCC(CO)OC(=O)CCCc2ccc(cc2)N=Nc2ccc(CCCC)cc2)cc1

References

Lichtenegger M, Tiapko O, Svobodova B, Stockner T, Glasnov TN, Schreibmayer W, Platzer D, de la Cruz GG, Krenn S, Schober R, Shrestha N, Schindl R, Romanin C, Groschner K. An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel. Nat Chem Biol. 2018 Apr;14(4):396-404. doi: 10.1038/s41589-018-0015-6. Epub 2018 Mar 19. PubMed PMID: 29556099; PubMed Central PMCID: PMC5903546.