TargetMol

ORC-13661 HCl

Product Code:
 
TAR-T33815
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33815-5mg5mg£850.00
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Quantity:
TAR-T33815-50mg50mg£1,661.00
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Quantity:
TAR-T33815-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Orc-13661 (BNP-13661) is a potent and well-tolerated oral active protective agent for the prevention of aminogrogycoside-induced hearing loss.
CAS:
1589571-77-6
Formula:
C18H20Cl2N4O2S
Molecular Weight:
427.34
Purity:
0.98
SMILES:
Cl.CN1C2CC[C@H]1c1sc(NC(=O)Nc3ccc(Cl)cc3)c(C(N)=O)c1C2

References

Chowdhury S, Owens KN, Herr RJ, Jiang Q, Chen X, Johnson G, Groppi VE, Raible DW, Rubel EW, Simon JA. Phenotypic Optimization of Urea-Thiophene Carboxamides to Yield Potent, Well Tolerated and Orally Active Protective Agents Against Aminoglycoside-Induced Hearing Loss. J Med Chem. 2017 Oct 9. doi: 10.1021/acs.jmedchem.7b00932. [Epub ahead of print] PubMed PMID: 28992413.