TargetMol

Org 2058

Product Code:
 
TAR-T33819
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33819-5mg5mg£850.00
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Further Information

Bioactivity:
Org 2058 is a synthetic progestin.
CAS:
24320-06-7
Formula:
C22H32O3
Molecular Weight:
344.495
Purity:
0.98
SMILES:
[H][C@@]12C[C@@H](CC)[C@H](C(=O)CO)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]

References

Geier A, Bella R, Beery R, Haimsohn M, Lunenfeld B. Differences in the association of the progesterone receptor ligated by antiprogestin RU38486 or progestin ORG 2058 to chromatin components. Biochim Biophys Acta. 1987 Oct 22;931(1):78-86. PubMed PMID: 3651513. Traish AM, Netsuwan N. 7 alpha-17 alpha-Dimethyl-19-nortestosterone (mibolerone) induces conformational changes in progesterone receptors distinct from those induced by ORG 2058. Steroids. 1994 Jun;59(6):362-70. PubMed PMID: 7940614. Geier A, Bella R, Beery R, Lunenfeld B. Comparison of the physical properties of the nuclear progesterone receptor, bound to antiprogestin RU 486 or progestin ORG 2058, following limited proteolysis. Steroids. 1990 Jun;55(6):283-8. PubMed PMID: 2385853. Bakos T, L?k?s M, Vincze I, Volford J. Steroids 51. An improved synthesis of ORG 2058 and the synthesis of [3H]ORG 2058. Steroids. 1993 Mar;58(3):115-8. PubMed PMID: 8475515.