TargetMol

PQ1

Product Code:
 
TAR-T34120
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34120-5mg5mg£1,251.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T34120-50mg50mg£2,464.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T34120-100mg100mg£3,283.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PQ1, as an enhancer of gap junction in SW480 human colorectal cancer cells can act by restoring GJIC and increasing connexin expression in breast cancer cell lines while not affecting normal mammary cells.
CAS:
1609196-55-5
Formula:
C21H22F3N3O3
Molecular Weight:
421.42
Purity:
0.98
SMILES:
COc1cc(NCCCN)c2[nH]c(=O)cc(C)c2c1Oc1cccc(c1)C(F)(F)F

References

de Oliveira LF, Santos C, Dos Reis Martinez CB. Biomarkers in the freshwater bivalve Corbicula fluminea confined downstream a domestic landfill leachate discharge. Environ Sci Pollut Res Int. 2016 Jul;23(14):13931-42. doi: 10.1007/s11356-016-6567-7. Epub 2016 Apr 4. PubMed PMID: 27040540. Chang CJ, Cheng CC, Chen YC, Kao YH, Chen SA, Chen YJ. Gap junction modifiers regulate electrical activities of the sinoatrial node and pulmonary vein: Therapeutic implications in atrial arrhythmogenesis. Int J Cardiol. 2016 Oct 15;221:529-36. doi: 10.1016/j.ijcard.2016.07.027. Epub 2016 Jul 5. PubMed PMID: 27414735. Hamid MMA, Thriemer K, Elobied ME, Mahgoub NS, Boshara SA, Elsafi HMH, Gumaa SA, Hamid T, Abdelbagi H, Basheir HM, Marfurt J, Chen I, Gosling R, Price RN, Ley B. Low risk of recurrence following artesunate-Sulphadoxine-pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan. Malar J. 2018 Mar 16;17(1):117. doi: 10.1186/s12936-018-2266-9. PubMed PMID: 29548285; PubMed Central PMCID: PMC5857106. Onofri E, Mercuri M, Archer T, Rapp-Ricciardi M, Ricci S. Legal medical consideration of Alzheimer's disease patients' dysgraphia and cognitive dysfunction: a 6 month follow up. Clin Interv Aging. 2016 Mar 7;11:279-84. doi: 10.2147/CIA.S94750. eCollection 2016. PubMed PMID: 27022252; PubMed Central PMCID: PMC4788358.