TargetMol

Preussin

Product Code:
 
TAR-T34131
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T34131-5mg5mg£850.00
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Further Information

Bioactivity:
Preussin is a new hydroxypyrrolidine alkaloid from Aspergillus ochraceus.
CAS:
119463-16-0
Formula:
C21H35NO
Molecular Weight:
317.517
Purity:
0.98
SMILES:
CCCCCCCCCC1CC(O)C(Cc2ccccc2)N1C

References

Buttachon S, Ramos AA, In?cio ?, Dethoup T, Gales L, Lee M, Costa PM, Silva AMS, Sekeroglu N, Rocha E, Pinto MMM, Pereira JA, Kijjoa A. Bis-Indolyl Benzenoids, Hydroxypyrrolidine Derivatives and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Aspergillus candidus KUFA0062. Mar Drugs. 2018 Apr 6;16(4). pii: E119. doi: 10.3390/md16040119. PubMed PMID: 29642369; PubMed Central PMCID: PMC5923406. Si CM, Shao LP, Mao ZY, Zhou W, Wei BG. An efficient approach to trans-4-hydroxy-5-substituted 2-pyrrolidinones through a stereoselective tandem Barbier process: divergent syntheses of (3R,4S)-statines, (+)-preussin and (-)-hapalosin. Org Biomol Chem. 2017 Jan 18;15(3):649-661. doi: 10.1039/c6ob02523d. PubMed PMID: 27973631. Mao H, Jeong H, Yang J, Ha HJ, Yang JW. Preparation of Chiral Contiguous Epoxyaziridines and Their Regioselective Ring-Opening for Drug Syntheses. Chemistry. 2018 Feb 16;24(10):2370-2374. doi: 10.1002/chem.201706161. Epub 2018 Jan 25. PubMed PMID: 29314353. Rong HJ, Yao JJ, Li JK, Qu J. Molecular Iodine-Mediated ?-C-H Oxidation of Pyrrolidines to N,O-Acetals: Synthesis of (?)-Preussin by Late-Stage 2,5-Difunctionalizations of Pyrrolidine. J Org Chem. 2017 Jun 2;82(11):5557-5565. doi: 10.1021/acs.joc.7b00361. Epub 2017 May 18. PubMed PMID: 28497692.