TargetMol

Rumbrin

Product Code:
 
TAR-T34450
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T34450-5mg5mg£850.00
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Further Information

Bioactivity:
Rumbrin is a cytoprotective compound produced by Auxarthron umbrinum.
CAS:
148528-19-2
Formula:
C20H20ClNO3
Molecular Weight:
357.83
Purity:
0.98
SMILES:
COc1cc(oc(=O)c1C)C(C)=C/C=C/C=C/C=C/c1[nH]ccc1Cl

References

Yamagishi Y, Shindo K, Kawai H. Rumbrin, a new cytoprotective substance produced by Auxarthron umbrinum. II. Physico-chemical properties and structure determination. J Antibiot (Tokyo). 1993 Jun;46(6):888-91. PubMed PMID: 8344869. Clark BR, O'Connor S, Fox D, Leroy J, Murphy CD. Production of anticancer polyenes through precursor-directed biosynthesis. Org Biomol Chem. 2011 Sep 21;9(18):6306-11. doi: 10.1039/c1ob05667k. Epub 2011 Jul 26. PubMed PMID: 21792395. Yamagishi Y, Matsuoka M, Odagawa A, Kato S, Shindo K, Mochizuki J. Rumbrin, a new cytoprotective substance produced by Auxarthron umbrinum. I. Taxonomy, production, isolation and biological activities. J Antibiot (Tokyo). 1993 Jun;46(6):884-7. PubMed PMID: 8344868. Clark BR, Murphy CD. Biosynthesis of pyrrolylpolyenes in Auxarthron umbrinum. Org Biomol Chem. 2009 Jan 7;7(1):111-6. doi: 10.1039/b813236d. Epub 2008 Oct 31. PubMed PMID: 19081953.