Ryanodol

Product Code:

TAR-T34458

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

No additional charges, what you see is what you pay! *

Code	Size	Price

TAR-T34458-5mg

5mg

£850.00

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Quantity:

Prices exclude any Taxes / VAT

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Further Information

Bioactivity:

Ryanodol is a complex diterpenoid that modulates intracellular calcium-ion release at ryanodine receptors, ion channels critical for skeletal and cardiac muscle excitation-contraction coupling and synaptic transmission.

CAS:

6688-49-9

Formula:

C20H32O8

Molecular Weight:

400.468

Purity:

0.98

SMILES:

CC(C)[C@@]1(O)[C@@H](O)[C@@]2(O)[C@@]3(C)C[C@]4(O)O[C@@]5([C@H](O)[C@@H](C)CC[C@]35O)[C@@]2(O)[C@]14C

Documents

References

Masuda K, Nagatomo M, Inoue M. Chemical Conversion of Ryanodol to Ryanodine. Chem Pharm Bull (Tokyo). 2016 Jul 1;64(7):874-9. doi: 10.1248/cpb.c16-00214. Epub 2016 Mar 23. PubMed PMID: 27010543. Chuang KV, Xu C, Reisman SE. A 15-step synthesis of (+)-ryanodol. Science. 2016 Aug 26;353(6302):912-5. doi: 10.1126/science.aag1028. PubMed PMID: 27563092; PubMed Central PMCID: PMC5505075. Nagatomo M, Koshimizu M, Masuda K, Tabuchi T, Urabe D, Inoue M. Total synthesis of ryanodol. J Am Chem Soc. 2014 Apr 23;136(16):5916-9. doi: 10.1021/ja502770n. Epub 2014 Apr 11. PubMed PMID: 24708178. Masuda K, Koshimizu M, Nagatomo M, Inoue M. Asymmetric Total Synthesis of (+)-Ryanodol and (+)-Ryanodine. Chemistry. 2016 Jan 4;22(1):230-6. doi: 10.1002/chem.201503641. Epub 2015 Nov 30. PubMed PMID: 26616265.