SC 4453

Product Code:

TAR-T34554

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T34554-5mg

5mg

£850.00

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Quantity:

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Further Information

Bioactivity:

SC 4453 is a digoxin analog and a cardiac glycoside derivative.

CAS:

59712-21-9

Formula:

C41H64N2O12

Molecular Weight:

776.965

Purity:

0.98

SMILES:

[H][C@]12CC[C@]3([H])[C@@]([H])(C[C@H](O)[C@]4(C)[C@@H](CC[C@]34O)c3ccnnc3)[C@@]1(C)CC[C@H](C2)O[C@H]1C[C@H](O)[C@H](O[C@@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](O)[C@@H](O)[C@H](C)O3)[C@H](C)O2)[C@@H](C)O1

Documents

References

Randimbivololona F, Lesne M. Importance of the urinary excretion in the total elimination of SC4453 in the guinea-pig. J Pharmacol. 1984 Apr-Jun;15(2):199-208. PubMed PMID: 6738077. Gupta RS, Chopra A. Cross-resistance and biochemical studies with two classes of HeLa cell mutants resistant to cardiac glycosides. The unusual behavior of cardenolide SC4453. J Biol Chem. 1985 Jun 10;260(11):6843-50. PubMed PMID: 2987235. Randimbivololona F, Lesne M. Intestinal absorption of SC4453 in the guinea-pig. Arch Int Pharmacodyn Ther. 1982 Dec;260(2):296-8. PubMed PMID: 7165435. Randimbivololona F. Distribution of SC-4453, a new semi-synthetic derivative of digoxin, following an infusion preceded by an i.v. loading dose in the guinea-pig. Binding to plasma proteins. Eur J Drug Metab Pharmacokinet. 1988 Jan-Mar;13(1):19-22. PubMed PMID: 3396609.