TargetMol

SNAP-8719

Product Code:
 
TAR-T34666
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T34666-5mg5mg£850.00
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Quantity:
TAR-T34666-50mg50mg£1,661.00
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Quantity:
TAR-T34666-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
SNAP-8719 is a selective antagonist of α1D-AR. SNAP-8719 showed better selectivity for α1D-AR and lower binding affinity for the 5-HT1A receptor.
CAS:
255893-38-0
Formula:
C22H29ClF3N3O2
Molecular Weight:
459.94
Purity:
0.98
SMILES:
Cl.C[C@H](CN1CCN(CC1)c1cc(F)c(F)cc1F)N1C(=O)CC2(CCCC2)CC1=O

References

Sakauchi N, Kohara Y, Sato A, Suzaki T, Imai Y, Okabe Y, Imai S, Saikawa R, Nagabukuro H, Kuno H, Fujita H, Kamo I, Yoshida M. Discovery of 5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carb oxamide (TAK-259), as a Novel, Selective, and Orally Active ?1D Adrenoceptor Antagonist with Anti-urinary Frequency Effects: Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities. J Med Chem. 2016 Mar 8. [Epub ahead of print] PubMed PMID: 26954848.