TargetMol

SNIPER(CRABP)-11

Product Code:
 
TAR-T34671
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T34671-5mg5mg£850.00
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Further Information

Bioactivity:
SNIPER(CRABP)-11 is a potent protein degrader. SNIPER(CRABP)-11 displayed degradation activity toward the mitochondrial CRABP-II protein.
CAS:
1384275-50-6
Formula:
C60H83N7O10
Molecular Weight:
1062.363
Purity:
0.98
SMILES:
CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)NCCOCCOCCNC(=O)CON=C1CCC(C)(C)C(C=CC(C)=CC=CC(C)=CC(O)=O)=C1C

References

Okuhira K, Shoda T, Omura R, Ohoka N, Hattori T, Shibata N, Demizu Y, Sugihara R, Ichino A, Kawahara H, Itoh Y, Ishikawa M, Hashimoto Y, Kurihara M, Itoh S, Saito H, Naito M. Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules. Mol Pharmacol. 2017 Mar;91(3):159-166. doi: 10.1124/mol.116.105569. Epub 2016 Dec 13. PubMed PMID: 27965304.