TargetMol

TH9402

Product Code:
 
TAR-T34833
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T34833-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
TH9402 is a dibrominated rhodamine derivative and potent photosensitizer and useful in photodynamic therapy. TH9402 eradicates multiple myeloma (MM) and BC cell lines, while sparing more than 50% of normal pluripotential blood stem cells from healthy volunteers. TH9402 offers an excellent potential as an ex vivo photodynamic purging agent for autologous transplantation in MM and BC treatment.
CAS:
174230-05-8
Formula:
C21H15Br2ClN2O3
Molecular Weight:
538.62
Purity:
0.98
SMILES:
[Cl-].COC(=O)c1ccccc1-c1c2ccc(N)c(Br)c2[o+]c2c(Br)c(N)ccc12

References

Tregs served sunny-side up By Betts, Brian C.; Young, James W. From Blood (2010), 116(23), 4736-4737. Quaternized phthalocyanines and method for photodisinfection of water By Vorozhtsov, G. N.; Kaliya, O. L.; Kuznetsova, N. A.; Luzhkov, Yu. M.; Luk'yanets, E. A.; Makarov, D. A.; Negrimovskii, V. M.; Slivka, L. K.; Yuzhakova, O. A. From Russ. (2006), RU 2281953 C1 20060820. Photodynamic purging of alloreactive T cells for adoptive immunotherapy after haploidentical stem cell transplantation By Perruccio, Katia; Topini, Fabiana; Tosti, Antonella; Carotti, Alessandra; Aloisi, Teresa; Aversa, Franco; Martelli, Massimo F.; Velardi, Andrea From Blood Cells, Molecules, & Diseases (2008), 40(1), 76-83. A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique By Mielke, Stephan; Nunes, Raquel; Rezvani, Katayoun; Fellowes, Vicki S.; Venne, Annie; Solomon, Scott R.; Fan, Yong; Gostick, Emma; Price, David A.; Scotto, Christian; et al From Blood (2008), 111(8), 4392-4402.