TargetMol

Tiliacorine

Product Code:
 
TAR-T34879
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34879-5mg5mg£850.00
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Further Information

Bioactivity:
Tiliacorine is a dibenzodioxin biphenylalkaloid.
CAS:
27073-72-9
Formula:
C36H38N2O5
Molecular Weight:
578.709
Purity:
0.98
SMILES:
COc1ccc2Cc1c1Cc(C[C@H]3N(C)CCc4cc5Oc6c(OC)cc7CCN(C)[C@@H](C2)c7c6Oc5cc34)ccc1O

References

Dwuma-Badu D, Ayim JS, Fiagbe NY, Tackie AN, Knapp JE, Slatkin DJ, Schiff PL Jr. DIOXINS/*ISOLof West African medicinal plants. XV. Dinklacorine, a new biphenyl dibenzodioxin alkaloid from Tiliacora dinklagei. Lloydia. 1976 Jul-Aug;39(4):213-7. PubMed PMID: 957910. Sureram S, Senadeera SP, Hongmanee P, Mahidol C, Ruchirawat S, Kittakoop P. Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2902-5. doi: 10.1016/j.bmcl.2012.02.053. Epub 2012 Feb 23. PubMed PMID: 22418278. Seal T, Mukherjee B. (+)-Tiliarine, a selective in vitro inhibitor of human melanoma cells. Phytother Res. 2002 Sep;16(6):596-9. PubMed PMID: 12237824. Nayak T, Jena L, Waghmare P, Harinath BC. Identification of potential inhibitors for mycobacterial uridine diphosphogalactofuranose-galactopyranose mutase enzyme: A novel drug target through in silico approach. Int J Mycobacteriol. 2018 Jan-Mar;7(1):61-68. doi: 10.4103/ijmy.ijmy_174_17. PubMed PMID: 29516888.