TargetMol

Dasabuvir

Product Code:
 
TAR-T3489
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3489-2mg2mg£97.00
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TAR-T3489-5mg5mg£112.00
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TAR-T3489-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T3489-10mg10mg£132.00
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TAR-T3489-25mg25mg£182.00
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TAR-T3489-50mg50mg£250.00
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Quantity:
TAR-T3489-100mg100mg£367.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dasabuvir is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intracellular uptake, dasabuvir binds HCV NS5B polymerase and blocks viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.
CAS:
1132935-63-7
Formula:
C26H27N3O5S
Molecular Weight:
493.58
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.9962
SMILES:
COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc(NS(C)(=O)=O)ccc2c1
Target:
HCV Protease

References

Kati W, et al. In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2015 Mar;59(3):1505-11. Hayashi T, Murakami K, Hirano J, et al. Dasabuvir inhibits human norovirus infection in human intestinal enteroids. mSphere. 2021, 6(6): e00623-21.