TargetMol

UK 1745

Product Code:
 
TAR-T34987
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34987-5mg5mg£1,167.00
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This product comes from: United States.
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Further Information

Bioactivity:
UK 1745 is a novel drug of cardiotonic.
CAS:
170684-14-7
Formula:
C16H23ClN2O2
Molecular Weight:
310.82
Purity:
0.98
SMILES:
Cl.C[C@H]1c2cc(C)c3NC(=O)C(C)(C)c3c2O[C@@]1(C)CN

References

Sawada H, Endoh M. Pharmacological characterization of effects of UK-1745, a novel cardiotonic agent with beta-adrenoceptor-blocking action, in aequorin-loaded canine right ventricular muscle. J Mol Cell Cardiol. 1999 May;31(5):1047-62. PubMed PMID: 10336843. Uchida Y, Kawada M, Sawanobori K, Sonoki H, Inoue K, Mizuno K, Itou T, Tabunoki Y, Tsukamoto M, Ohashi Y, Kyotani Y, Shimizu N, Fujii M, Nakamura M. Cardiovascular effects of (2RS,3SR)- 2-aminomethyl-2,3,7,8-tetrahydro-2,3,5,8,8-pentamethyl-6H-furo- [2,3-e]indol-7-one hydrochloride (UK-1745), a novel cardiotonic agent with vasodilatory and antiarrhythmic properties. Arzneimittelforschung. 1998 Mar;48(3):219-31. PubMed PMID: 9553677. Uemura H, Sakamoto N, Nakaya H. Electropharmacological effects of UK-1745, a novel cardiotonic drug, in guinea-pig ventricular myocytes. Eur J Pharmacol. 1999 Nov 3;383(3):361-71. PubMed PMID: 10594330.