TargetMol

VM4-037 F-18

Product Code:
 
TAR-T35067
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35067-5mg5mg£850.00
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Further Information

Bioactivity:
VM4-037 F-18 is a fluorinated PET imaging agent used for carbonic anhydrase IX.
CAS:
1071471-25-4
Formula:
C26H29FN6O7S2
Molecular Weight:
619.67
Purity:
0.98
SMILES:
CC(C)[C@@H](C(=O)N[C@@H](Cc1ccc(OCC[18F])cc1)C(O)=O)n1cc(COc2ccc3nc(sc3c2)S(N)(=O)=O)nn1

References

Peeters SG, Dubois L, Lieuwes NG, Laan D, Mooijer M, Schuit RC, Vullo D, Supuran CT, Eriksson J, Windhorst AD, Lambin P. [(18)F]VM4-037 MicroPET Imaging and Biodistribution of Two In Vivo CAIX-Expressing Tumor Models. Mol Imaging Biol. 2015 Oct;17(5):615-9. doi: 10.1007/s11307-015-0831-y. PubMed PMID: 25708744; PubMed Central PMCID: PMC4768225. Doss M, Kolb HC, Walsh JC, Mocharla VP, Zhu Z, Haka M, Alpaugh RK, Chen DY, Yu JQ. Biodistribution and radiation dosimetry of the carbonic anhydrase IX imaging agent [(18)?F]VM4-037 determined from PET/CT scans in healthy volunteers. Mol Imaging Biol. 2014 Oct;16(5):739-46. doi: 10.1007/s11307-014-0730-7. PubMed PMID: 24696183. Turkbey B, Lindenberg ML, Adler S, Kurdziel KA, McKinney YL, Weaver J, Vocke CD, Anver M, Bratslavsky G, Eclarinal P, Kwarteng G, Lin FI, Yaqub-Ogun N, Merino MJ, Linehan WM, Choyke PL, Metwalli AR. PET/CT imaging of renal cell carcinoma with (18)F-VM4-037: a phase II pilot study. Abdom Radiol (NY). 2016 Jan;41(1):109-18. doi: 10.1007/s00261-015-0599-1. PubMed PMID: 26830617.