TargetMol

Colesevelam Hydrochloride

Product Code:
 
TAR-T35371
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T35371-25mg25mgEnquire
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TAR-T35371-50mg50mgEnquire
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TAR-T35371-10mg10mg£102.00
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This product comes from: United States.
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Further Information

Bioactivity:
Colesevelam Hydrochloride is a bile acid sequestrant with a higher affinity for glycocholic acid in vitro. Colesevelam Hydrochloride inhibits bile acid reabsorption, leading to increased bile acid synthesis and reduces cholesterol levels in patients with
CAS:
182815-44-7
Formula:
C31H67Cl3N4O
Molecular Weight:
618.25
Purity:
0.98
SMILES:
Cl.[Cl-].NCC=C.ClCC1CO1.CCCCCCCCCCNCC=C.C[N+](C)(C)CCCCCCNCC=C

References

Cabr? N, Duan Y, Llorente C, et al. Colesevelam Reduces Ethanol-Induced Liver Steatosis in Humanized Gnotobiotic Mice. Cells. 2021;10(6):1496. Dean M Robinson, et al. Am J Cardiovasc Drugs . 2007;7(6):453-65. Potthoff MJ, Potts A, He T, et al. Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice. Am J Physiol Gastrointest Liver Physiol. 2013;304(4):G371-G380.