TargetMol

RBPJ Inhibitor-1

Product Code:
 
TAR-T35566
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35566-1mg1mg£98.00
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TAR-T35566-5mg5mg£135.00
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TAR-T35566-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T35566-10mg10mg£182.00
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TAR-T35566-25mg25mg£303.00
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TAR-T35566-50mg50mg£470.00
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Quantity:
TAR-T35566-100mg100mg£651.00
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This product comes from: United States.
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Further Information

Bioactivity:
RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation[1].
CAS:
0
Formula:
0
Molecular Weight:
0
Pathway:
Stem Cells|Neuroscience|Proteases/Proteasome
Purity:
0.98
SMILES:
0
Target:
Gamma-secretase

References

Milstein M, et al. RIN1 is a breast tumor suppressor gene. Cancer Res. 2007;67(24):11510-11516. Fujioka M, et al. Cloning of a novel splicing variant of RIN1 and its expression in gastric and colon cancer. Oncol Res. 2009;17(11-12):593-599. Hurtado C, et al. Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ. Sci Rep. 2019;9(1):10811.