TargetMol

Marcfortine A

Product Code:
 
TAR-T35745
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35745-5mg5mg£2,028.00
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This product comes from: United States.
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Further Information

Bioactivity:
Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.
CAS:
75731-43-0
Formula:
C28H35N3O4
Molecular Weight:
477.605
Purity:
0.98
SMILES:
CN1C(=O)C23CCCCN2CC11CC2(C(=O)Nc4c2ccc2OC(C)(C)C=COc42)C(C)(C)C1C3