TargetMol

CAY10410

Product Code:
 
TAR-T35811
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35811-5mg5mg£1,091.00
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TAR-T35811-50mg50mg£2,143.00
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Quantity:
TAR-T35811-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. 15-deoxy-δ12,14-PGJ2 has been shown to be a potent ligand for PPARγ. Metabolism of the cyclopentenone prostaglandins PGA2, PGJ2, and δ12-PGJ2 occurs via glutathione addition across the α,β unsaturated enone. CAY10410 was designed as an analog of the PPARγ-binding prostaglandins which could not undergo this conjugation reaction. In human neuroblastoma SH-SY5Y cells, CAY10410 was not cytotoxic at up to 25 μM. It also failed to covalently modify thioredoxin or induce oxidative stress at 50 μM.
CAS:
596104-94-8
Formula:
C20H30O3
Molecular Weight:
318.5
Purity:
0.98
SMILES:
O=C1/C([C@@H](C/C=CCCCC(O)=O)CC1)=C/C=CCCCCC