TargetMol

URB602

Product Code:
 
TAR-T3591
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3591-1mL1 mL * 10 mM (in DMSO)£94.00
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TAR-T3591-10mg10mg£102.00
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TAR-T3591-25mg25mg£122.00
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TAR-T3591-50mg50mg£161.00
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TAR-T3591-100mg100mg£230.00
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This product comes from: United States.
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Further Information

Bioactivity:
URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28?4 μM) through a noncompetitive mechanism.
CAS:
565460-15-3
Formula:
C19H21NO2
Molecular Weight:
295.382
Pathway:
Microbiology/Virology; Metabolism
Purity:
0.9981
SMILES:
O=C(Nc1cccc(c1)-c1ccccc1)OC1CCCCC1
Target:
Lipase; Antibacterial

References

King AR, et al. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chem Biol. 2007 Dec;14(12):1357-65. Guindon J, et al. Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. Br J Pharmacol. 2011 Aug;163(7):1464-78. Duncan M, et al. Distribution and function of monoacylglycerol lipase in the gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1255-65. Hohmann AG, et al. An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 Jun 23;435(7045):1108-12.