TargetMol

Celecoxib Carboxylic Acid

Product Code:
 
TAR-T36187
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36187-5mg5mg£174.00
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Quantity:
TAR-T36187-10mg10mg£238.00
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TAR-T36187-25mg25mg£468.00
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Quantity:
TAR-T36187-50mg50mg£815.00
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This product comes from: United States.
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Further Information

Bioactivity:
Celecoxib carboxylic acid is an inactive metabolite of the COX-2 inhibitor celecoxib .1,2It is formed from celecoxib primarily by the cytochrome P450 (CYP) isoform CYP2C9.
CAS:
170571-01-4
Formula:
C17H12F3N3O4S
Molecular Weight:
411.36
Purity:
0.98
SMILES:
NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(O)=O)C(F)(F)F

References

Kim, S.-H., Kim, D.-H., Byeon, J.-Y., et al.Effects of CYP2C9 genetic polymorphisms on the pharmacokinetics of celecoxib and its carboxylic acid metaboliteArch. Pharm. Res.40(3)382-390(2017) Liu, H., Huang, X., Shen, J., et al.Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: Molecular docking and 3D QSAR analysesJ. Med. Chem.45(22)4816-4827(2002)