TargetMol

Suc-Leu-Tyr-AMC

Product Code:
 
TAR-T36352
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36352-1mg1mg£102.00
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Quantity:
TAR-T36352-5mg5mg£137.00
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TAR-T36352-10mg10mg£182.00
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TAR-T36352-25mg25mg£265.00
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TAR-T36352-50mg50mg£386.00
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TAR-T36352-100mg100mg£547.00
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Quantity:
TAR-T36352-500mg500mg£1,107.00
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Quantity:
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Further Information

Bioactivity:
The calpains are a family of calcium-dependent cysteine proteases, with calpain I (μ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; emission max: 460 nm). Suc-Leu-Tyr-AMC can also be cleaved by the Ti protease from E. coli.
CAS:
94367-20-1
Formula:
C29H33N3O8
Molecular Weight:
551.6
Purity:
0.98
SMILES:
CC(C1=CC=C(C=C1O2)NC([C@H](CC3=CC=C(C=C3)O)NC([C@@H](NC(CCC(O)=O)=O)CC(C)C)=O)=O)=CC2=O

References

Woo KM, et al. Protease Ti from Escherichia coli requires ATP hydrolysis for protein breakdown but not for hydrolysis of small peptides. J Biol Chem. 1989;264(4):2088-2091.