TargetMol

(R)-Bromoenol lactone

Product Code:
 
TAR-T36838
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36838-5mg5mg£850.00
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Quantity:
TAR-T36838-50mg50mg£1,661.00
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Quantity:
TAR-T36838-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2β except at high doses of 20-30 μM. (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 μM.
CAS:
478288-90-3
Formula:
C16H13BrO2
Molecular Weight:
317.2
Purity:
0.98
SMILES:
Br/C=C(CC1)/OC([C@@]1([H])C2=CC=CC3=CC=CC=C32)=O