TargetMol

SARS-CoV MPro-IN-1

Product Code:
 
TAR-T37174
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37174-5mg5mg£850.00
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Quantity:
TAR-T37174-50mg50mg£1,661.00
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Quantity:
TAR-T37174-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.72 μM). MProinhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM.
CAS:
2413716-71-7
Formula:
C25H25FN4O4
Molecular Weight:
464.5
Purity:
0.98
SMILES:
O=C1NCC[C@H]1C[C@H](NC([C@@H](NC(C2=CC(C=CC=C3)=C3N2)=O)CC4=CC=CC(F)=C4)=O)C=O

References

Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main proteaseScience368(6497)1331-1335(2020)