TargetMol

Riluzole-13C,15N2

Product Code:
 
TAR-T37608
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37608-5mg5mg£1,112.00
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Further Information

Bioactivity:
Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.
CAS:
1215552-03-6
Formula:
C8H5F3N2OS
Molecular Weight:
237.17
Purity:
0.98
SMILES:
[15NH2][13c]1[15n]c2ccc(OC(F)(F)F)cc2s1