TargetMol

7-Ethoxy-4-(trifluoromethyl)coumarin

Product Code:
 
TAR-T37926
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37926-5mg5mg£104.00
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TAR-T37926-10mg10mg£129.00
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TAR-T37926-25mg25mg£185.00
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Quantity:
TAR-T37926-50mg50mg£232.00
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This product comes from: United States.
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Further Information

Bioactivity:
7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively.
CAS:
115453-82-2
Formula:
C12H9F3O3
Molecular Weight:
258.196
Purity:
0.98
SMILES:
CCOc1ccc2c(cc(=O)oc2c1)C(F)(F)F

References

Buters, J.T.M., Schiller, C.D., and Chou, R.C.A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarinBiochem. Pharmacol.46(9)1577-1584(1993)