TargetMol

(R)-Fadrozole

Product Code:
 
TAR-T38424
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38424-5mg5mg£850.00
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Quantity:
TAR-T38424-50mg50mg£1,661.00
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Quantity:
TAR-T38424-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
(R)-Fadrozole ((R)-CGS 16949A; FAD286) is a potent nonsteroidal inhibitor. (R)-Fadrozole also inhibits human placental aromatase (pIC 50 = 6.17) and aldosterone biosynthesis. (R)-Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats..
CAS:
102676-87-9
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Furet P, et al. Aromatase inhibitors: synthesis, biological activity, and binding mode of azole-type compounds. J Med Chem. 1993;36(10):1393-1400. Minnaard-Huiban M, et al. Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats: discordant enantioselectivity versus reduction of plasma aldosterone. Endocrinology. 2008;149(1):28-31.