TargetMol

Erianin

Product Code:
 
TAR-T3864
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3864-5mg5mg£103.00
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TAR-T3864-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T3864-10mg10mg£124.00
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TAR-T3864-25mg25mg£148.00
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TAR-T3864-50mg50mg£177.00
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TAR-T3864-100mg100mg£228.00
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Further Information

Bioactivity:
Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metabolism in a JNK/SAPK-dependent manner and inducing endothelial cytoskeletal disorganisation. Erianin shows potent inhibitory activity on the proliferation of HL-60 cells, the inhibition might be relative to the apoptosis induced by Erianin and the altered expression of bcl-2 and bax genes in HL-60 cells.
CAS:
95041-90-0
Formula:
C18H22O5
Molecular Weight:
318.369
Pathway:
Apoptosis; Microbiology/Virology
Purity:
0.9822
SMILES:
COc1ccc(CCc2cc(OC)c(OC)c(OC)c2)cc1O
Target:
BCL; Antibacterial

References

Zhou H,et al. Liquid chromatographic-mass spectrometry analysis and pharmacokinetic studies of erianin for intravenous injection in dogs. Arzneimittelforschung. 2009;59(3):141-5. Lam F,et al. ZJU-6, a novel derivative of Erianin, shows potent anti-tubulin polymerisation and anti-angiogenic activities. Invest New Drugs. 2012 Oct;30(5):1899-907.